Gene expression regulated by G-actin switch

GSE17105

Mus musculus

9 Downloadable Samples

Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Submitter Supplied Information

Description

We analysed the G-actin regulated transcriptome by gene expression analysis using previously characterised actin binding drugs. We found many known MAL/MRTF-dependent target genes of serum response factor (SRF) as well as unknown directly regulated genes.

PubMed ID

19683494

Publication Title

Negative regulation of the EGFR-MAPK cascade by actin-MAL-mediated Mig6/Errfi-1 induction.

Total Samples

Submitter’s Institution

Max-Planck-Institute of Biochemistry

Authors

Descot A, Hoffmann R, Shaposhnikov D, Reschke M, Ullrich A, Posern G

Source Repository

Gene Expression Omnibus (GEO)

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