Gene Expression Analysis of Ara-C Resistance in AML

GSE18322

Mus musculus

12 Downloadable Samples

Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Submitter Supplied Information

Description

Using two independently derived murine BXH2 cell lines, Ara-C resistant derivatives were developed by exposure to increasing concentrations of Ara-C. Microarray analysis comparing the Ara-C resistant cells to their Ara-C sensitive parental cell lines identified potential genes involved in Ara-C resistance.

PubMed ID

20508618

Publication Title

Deoxycytidine kinase is downregulated in Ara-C-resistant acute myeloid leukemia murine cell lines.

Total Samples

Submitter’s Institution

The University of Minnesota

Authors

Rathe SK, Largaespada DA

Source Repository

Gene Expression Omnibus (GEO)

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