Gene expression profiling of ovaries collected from wild type (WT) mice and progesterone receptor (PR) knock out mice

Previous studies have shown that PR is a critical regulator of ovulation. The PR-null mice (PRKO) failed to ovulate due to a failure in the rupture of the preovulatory follicles.

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Nallasamy S, Kim J, Sitruk-Ware R, Bagchi M, Bagchi I