Zbtb20-mediated repression of genes in developing CA1 pyramidal neurons

GSE38837

Mus musculus

6 Downloadable Samples

Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Submitter Supplied Information

Description

The transcriptional repressor Zbtb20 is essential for specification of hippocampal CA1 pyramidal neurons. Moreover, ectopic expression of Zbtb20 is sufficient to transform subicular and retrosplenial areas of D6/Zbtb20S mice to CA1. We used microarrays to identify genes that are repressed by Zbtb20 in developing CA1 pyramidal neurons in the CA1-transformed cortex of D6/Zbtb20S mice.

PubMed ID

23283686

Publication Title

Zbtb20 defines a hippocampal neuronal identity through direct repression of genes that control projection neuron development in the isocortex.

Total Samples

Submitter’s Institution

Odense University Hospital

Authors

Nielsen JV, Thomassen M, Møllgård K, Noraberg J, Jensen NA

Source Repository

Gene Expression Omnibus (GEO)

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