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Accession IconGSE67227

Gene Expression in mice liver after knockdown of Rab5

Organism Icon Mus musculus
Sample Icon 1 Downloadable Sample
Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

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Description
RNAi-mediated silencing of Rab5 and the consequent loss of endosomes in the mouse liver caused severe metabolic defects such as hypoglycemia, hepatomegaly, hypercholesterolemia, hyperlipidemia and glycogen accumulation.
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