This SuperSeries is composed of the SubSeries listed below.
Age- and pregnancy-associated DNA methylation changes in mammary epithelial cells.
Sex, Age, Specimen part
View SamplesTBR1 is a forebrain specific T-box transcription factor. Tbr1-/- mice have been characterized by defective axonal projections from cerebral cortex and abnormal neuronal migration of cerebral cortex and amygdala.
Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality.
No sample metadata fields
View SamplesCigarette smoke (CS) is one of risk factor to chronic obstructive pulmonary disease that is the major causes of death in the world. Furthermore, CS is an independent risk factor for chronic kidney disease (CKD) in the general adult population. The goal of this project was to identified the mechanisms of renal damage that might be associated with exposure to CS extract (CSE) in human kidney proximal tubular epithelial cell line (HK-2 cells) cells. Overall design: RNA sequencing of human kidney proximal tubular epithelial cell line (HK-2 cells) after 24 hours exposure to 0.6% CSE.
Cigarette Smoke Exposure Increases Glucose-6-phosphate Dehydrogenase, Autophagy, Fibrosis, and Senescence in Kidney Cells In Vitro and In Vivo.
Specimen part, Treatment, Subject
View SamplesA series contains a set of transcript intensity values measured by Affymetrix microarray.
Systems-level analysis of cell-specific AQP2 gene expression in renal collecting duct.
Sex, Specimen part
View SamplesThis series of microarray data contain transcript intensity of mpkCCD cells.
Systems-level analysis of cell-specific AQP2 gene expression in renal collecting duct.
No sample metadata fields
View SamplesRNA from wt and SIN1 knock-out MEF cell lines were compared
mTORC2 Responds to Glutamine Catabolite Levels to Modulate the Hexosamine Biosynthesis Enzyme GFAT1.
Specimen part
View SamplesG1ME cells are GATA1-deficient murine bipotential megakaryocyte/erythrocyte progenitor cells derived from Gata1-negative murine ES cells. In order to assess the impact of GATA1 on gene regulation and cell differentiation, an expression construct was used to transiently produce high levels of GATA1. Cells transduced with this construct or a vector control were harvested at 18 and 42 hours, and gene expression was analyzed using Affymetrix MOE430 version 2 arrays.
Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate.
Cell line
View SamplesThe purpose of this study was to analyze the genomic signatures and profiles of skin from ichthyosis (various subtypes) vs. healthy patients. The analysis strategy was to study differentially expressed genes common to the ichthyosis shared phenotype, as well as individual ichthyosis subtypes, and compare and contrast to the genomic profiles of atopic dermatitis and psoriasis.
Ichthyosis molecular fingerprinting shows profound T<sub>H</sub>17 skewing and a unique barrier genomic signature.
Age, Specimen part, Disease
View SamplesThis SuperSeries is composed of the SubSeries listed below.
Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors.
Specimen part, Cell line
View SamplesThis SuperSeries is composed of the SubSeries listed below.
MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma.
Treatment, Time
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