publication_authors:Driscoll DR Results

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Microarray (44)

Platform

Affymetrix Mouse Genome 430 2.0 Array (mouse4302) (41)

Affymetrix Zebrafish Genome Array (zebrafish) (3)

Includes Publication

GSE83196

Beta-catenin-regulated genes in pancreatic cancer cells

Mus musculus
6 Downloadable Samples

Description

Activation of the canonical Wnt signaling pathway is commonly observed in pancreatic cancer. We therefore sought to identify a gene expression profile associated with the activation of this pathway in pancreatic cancer cells.

Publication Title

Activation of WNT/β-Catenin Signaling Enhances Pancreatic Cancer Development and the Malignant Potential Via Up-regulation of Cyr61.

Sample Metadata Fields

Specimen part, Cell line

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GSE16801

Comparative gene expression analysis of 2 subpopulations of dermal papilla cells.

Mus musculus
9 Downloadable Samples

Description

Different types of hair follicles can be found in the skin of mice. It is believed that the signals that control hair follicle differentiation arise from cells in a structure called the dermal papilla. Understanding the nature of those signals is of interest for the biology of the normal tissue.

Publication Title

Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis.

Sample Metadata Fields

No sample metadata fields

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GSE26809

FMRP Associates with Polyribosomes

Mus musculus
26 Downloadable Samples

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism.

Sample Metadata Fields

Sex, Specimen part

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GSE26745

Comparison of total and polyribosome-associated mRNA levels in male Fmr1 KO mice and male WT littermates

Mus musculus
24 Downloadable Samples

Description

The Fragile X Mental Retardation Protein, FMRP, is thought to regulate the translation of a specific set of neuronal mRNAs on polyribosomes. Therefore, we prepared polyribosomes on sucrose gradients and purified mRNA specifically from these fractions, as well as the total mRNA levels, to determine whether a set of mRNAs might be changed in its % association with polyribosomes in the absence of FMRP in the KO mouse model.