publication_authors:Mahoney J Results

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Microarray (102)

Platform

Affymetrix Mouse Genome 430 2.0 Array (mouse4302) (102)

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GSE18308

FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis

Mus musculus
6 Downloadable Samples

Description

FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis

Publication Title

FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis.

Sample Metadata Fields

Cell line

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GSE19372

Expression time series during the differentiation of ventral motor neurons from embryonic stem cells

Mus musculus
17 Downloadable Samples

Description

The aim of this study is to profile gene expression dynamics during the in vitro differentiation of embryonic stem cells into ventral motor neurons. Expression levels were profiled using Affymetrix microarrays at six timepoints during in vitro differentiation: ES cells (Day 0), embryoid bodies (Day 2), retinoid induction of neurogenesis (Day 2 +8hours of exposure to retinoic acid), neural precursors (Day 3), progenitor motor neurons (Day 4), postmitotic motor neurons (Day 7).

Publication Title

Ligand-dependent dynamics of retinoic acid receptor binding during early neurogenesis.

Sample Metadata Fields

Cell line

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GSE5198

Transcriptional profiling of mouse ileum in response to colonization with a zebrafish or mouse gut microbiota

Mus musculus
18 Downloadable Samples

Description

We compared gene expression in the small intestine (ileum) of mice that were either (i) germ-free, (ii) colonized with a conventional mouse cecal microbiota, (iii) colonized with a conventional zebrafish gut microbiota, or (iv) colonized with Pseudomonas aeruginosa PAO1.

Publication Title

Reciprocal gut microbiota transplants from zebrafish and mice to germ-free recipients reveal host habitat selection.

Sample Metadata Fields

Specimen part

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GSE9024

Gene activation by Rag-mediated DNA double strand breaks

Mus musculus
20 Downloadable Samples

Description

The objective is to identify genes that are differentially expressed following the introduction of DNA double strand breaks (DSBs) by the Rag proteins in murine pre-B cells. Cells lacking Artemis are used since the Rag-induced DSBs will not be repaired and, thus, will provide a continuous stimulus to the cell. Cells lacking Artemis and Atm are used to determine which gene expression changes depend on Atm and cells lacking Artemis that express an I kappa B alpha dominant negative are used to determine which gene expression changes depend on NFkB.