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accession-icon GSE34963
The Polycomb Repressive Complex 2 Is Required For MLL-AF9 Leukemia
  • organism-icon Mus musculus
  • sample-icon 18 Downloadable Samples
  • Technology Badge Icon

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Polycomb repressive complex 2 is required for MLL-AF9 leukemia.

Sample Metadata Fields

Specimen part, Disease, Disease stage

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accession-icon GSE34959
Expression profiling of primary wild type (WT), Ezh2-null and Eed-null murine MLL-AF9 AML
  • organism-icon Mus musculus
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon

Description

We evaluated gene expression changes in murine leukemia caused by retroviral overexpression of MLL-AF9. We compared wild-type (WT) leukemia cells with mutant leukemia cells after cre-mediated inactivation of homozygous conditional alleles for Ezh2 or Eed, both of which are components of the Polycomb Repressive Complex2.

Publication Title

Polycomb repressive complex 2 is required for MLL-AF9 leukemia.

Sample Metadata Fields

Specimen part, Disease, Disease stage

View Samples
accession-icon GSE34961
Expression profiling of secondary wild type (WT) and Ezh2-null murine MLL-AF9 AML
  • organism-icon Mus musculus
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon

Description

We evaluated gene expression changes in secondary recipient murine leukemia caused by retroviral overexpression of MLL-AF9. We compared wild-type (WT) leukemia cells with mutant leukemia cells after cre-mediated inactivation of a homozygous conditional allele for Ezh2, a component of the Polycomb Repressive Complex2.

Publication Title

Polycomb repressive complex 2 is required for MLL-AF9 leukemia.

Sample Metadata Fields

Specimen part, Disease, Disease stage

View Samples
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