It has been reported that repeated intra-tracheal instillation of S. chartarum spores induced significant pulmonary arterial remodeling in mice, which resulted in pathological changes like human pulmonary arterial hypertension (PAH) and elevation right ventricle systolic pressure.
Gene expression analysis of a murine model with pulmonary vascular remodeling compared to end-stage IPAH lungs.
Sex, Specimen part, Disease, Disease stage
View SamplesInvestigation of whole genome gene expression level changes in OASIS KO calvaria compared to wild-type calvaria.
Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation.
Specimen part
View SamplesCumulus-oocyte complexes were isolated a seperate time-points to generate temporal complexes. Targets from two biological replicates at each time point (0h, 8h, 16h post-hCG treatment) were generated and the expression profiles were determined using Affymetrix GeneChip Mouse Genome 430 2.0 Arrays. Comparisons between the sample groups allow the identification of genes with temporal expression patterns.
Gene expression profiles of cumulus cell oocyte complexes during ovulation reveal cumulus cells express neuronal and immune-related genes: does this expand their role in the ovulation process?
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