Description

It has been reported that repeated intra-tracheal instillation of S. chartarum spores induced significant pulmonary arterial remodeling in mice, which resulted in pathological changes like human pulmonary arterial hypertension (PAH) and elevation right ventricle systolic pressure.

Publication Title

Gene expression analysis of a murine model with pulmonary vascular remodeling compared to end-stage IPAH lungs.

Sample Metadata Fields

Sex, Specimen part, Disease, Disease stage