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accession-icon GSE71090
Expression data from isogenic Pten WT or KO mouse T-ALLs
  • organism-icon Mus musculus
  • sample-icon 12 Downloadable Samples
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Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia.

Sample Metadata Fields

Specimen part

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accession-icon GSE71087
Expression data from isogenic Pten WT or KO mouse T-ALLs treated with DBZ or DMSO
  • organism-icon Mus musculus
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon

Description

To investigate the underlying mechanisms mediating resistance to NOTCH inhibition in Pten-null T-ALL tumor cells we performed gene expression profiling of isogenic Pten-positive and Pten-deleted leukemia lymphoblasts after acute treatment with DBZ in vivo.

Publication Title

Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia.

Sample Metadata Fields

Specimen part

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