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GSE67358
Mus musculus
18 Downloadable Samples
Description
The TP53 transcription factor is frequently mutated at later stages of epithelial cancers, indicating a possible role in their invasion and metastasis. Importantly, in most cases rather than a simple loss of function p53 mutation, point mutations of p53 accumulate at the protein level and may have dominant negative functions. This study analyses gene expression differences between mice harbouring p53 mutation who do and do not develop metastasis.
Publication Title
Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy.
Sample Metadata Fields
No sample metadata fields
View Samples- Mus musculus, Homo sapiens
- 30 Downloadable Samples
Description
This SuperSeries is composed of the SubSeries listed below.
Publication Title
Gene-chip studies of adipogenesis-regulated microRNAs in mouse primary adipocytes and human obesity.
Sample Metadata Fields
Age, Specimen part
View Samples- Danio rerio
- 3 Downloadable Samples
Description
This SuperSeries is composed of the SubSeries listed below.
Publication Title
Zebrafish Pou5f1-dependent transcriptional networks in temporal control of early development.
Sample Metadata Fields
No sample metadata fields
View Samples- Saccharomyces cerevisiae
- 68 Downloadable Samples
- Affymetrix Yeast Genome 2.0 Array (yeast2)
Description
The SAGA co-activator has been implicated in the regulation of a smal subset of genes in budding yeast in transcriptomic analyses performed in steady-state levels of RNA.
Publication Title
SAGA Is a General Cofactor for RNA Polymerase II Transcription.
Sample Metadata Fields
Genetic information
View Samples- Saccharomyces cerevisiae
- 68 Downloadable Samples
- Affymetrix Yeast Genome 2.0 Array (yeast2)
Description
The SAGA co-activator has been implicated in the regulation of a smal subset of genes in budding yeast in transcriptomic analyses performed in steady-state levels of RNA.
Publication Title
SAGA Is a General Cofactor for RNA Polymerase II Transcription.
Sample Metadata Fields
Genetic information
View Samples- Saccharomyces cerevisiae
- 68 Downloadable Samples
- Affymetrix Yeast Genome 2.0 Array (yeast2)
Description
The SAGA co-activator has been implicated in the regulation of a smal subset of genes in budding yeast in transcriptomic analyses performed in steady-state levels of RNA.
Publication Title
SAGA Is a General Cofactor for RNA Polymerase II Transcription.
Sample Metadata Fields
Genetic information
View Samples- Saccharomyces cerevisiae
- 68 Downloadable Samples
- Affymetrix Yeast Genome 2.0 Array (yeast2)
Description
The SAGA co-activator has been implicated in the regulation of a smal subset of genes in budding yeast in transcriptomic analyses performed in steady-state levels of RNA.
Publication Title
SAGA Is a General Cofactor for RNA Polymerase II Transcription.
Sample Metadata Fields
Genetic information
View Samples- Saccharomyces cerevisiae
- 68 Downloadable Samples
- Affymetrix Yeast Genome 2.0 Array (yeast2)
Description
The SAGA co-activator has been implicated in the regulation of a smal subset of genes in budding yeast in transcriptomic analyses performed in steady-state levels of RNA.
Publication Title
SAGA Is a General Cofactor for RNA Polymerase II Transcription.
Sample Metadata Fields
Genetic information
View Samples- Saccharomyces cerevisiae
- 68 Downloadable Samples
- Affymetrix Yeast Genome 2.0 Array (yeast2)
Description
The SAGA co-activator has been implicated in the regulation of a smal subset of genes in budding yeast in transcriptomic analyses performed in steady-state levels of RNA.
Publication Title
SAGA Is a General Cofactor for RNA Polymerase II Transcription.
Sample Metadata Fields
Genetic information
View Samples- Saccharomyces cerevisiae
- 68 Downloadable Samples
- Affymetrix Yeast Genome 2.0 Array (yeast2)
Description
The SAGA co-activator has been implicated in the regulation of a smal subset of genes in budding yeast in transcriptomic analyses performed in steady-state levels of RNA.
Publication Title
SAGA Is a General Cofactor for RNA Polymerase II Transcription.
Sample Metadata Fields
Genetic information
View Samples