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accession-icon GSE28437
Expression data from mouse small intestinal intraepithelial lymphocytes
  • organism-icon Mus musculus
  • sample-icon 4 Downloadable Samples
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Description

The mammalian gastrointestinal tract harbors thousands of bacterial species that include symbionts as well as potential pathogens. The immune responses that limit access of these bacteria to underlying tissue remain poorly defined.

Publication Title

Gammadelta intraepithelial lymphocytes are essential mediators of host-microbial homeostasis at the intestinal mucosal surface.

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accession-icon GSE51089
Expression data from E12.5 and E14.5 mouse embryonic gonad of wild type (WT) and Wnt-4 knock-out (KO) mice. [Mouse430_2]
  • organism-icon Mus musculus
  • sample-icon 16 Downloadable Samples
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Description

Wnt-4 signaling is critical for embryonic female sexual development. When Wnt-4 gene is deleted during embryonic development, the knock-out females present a partial sex reversal.

Publication Title

Identification of the genes regulated by Wnt-4, a critical signal for commitment of the ovary.

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accession-icon GSE23556
Mx-Cre mediated deletion of SRF in murine hematopoietic LSK (Lin-Sca1+c-Kit+) cells
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
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Description

Analysis of hematopoietic LSK(Lin-Sca1+c-Kit+) cells lacking the Serum response factor (SRF) gene. Results provide insight into the role of SRF in regulating genetic programs important for hematopoietic stem cell development

Publication Title

The transcription factor Srf regulates hematopoietic stem cell adhesion.

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