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accession-icon GSE51250
Combined targeting of JAK2 and Bcl-xL/Bcl-2 as a novel curative treatment for malignancies expressing mutant JAK2 and overcoming acquired resistance to single agent JAK2 inhibitors
  • organism-icon Mus musculus
  • sample-icon 9 Downloadable Samples
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Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Combined targeting of JAK2 and Bcl-2/Bcl-xL to cure mutant JAK2-driven malignancies and overcome acquired resistance to JAK2 inhibitors.

Sample Metadata Fields

Specimen part, Disease, Disease stage

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accession-icon GSE17726
LAPC cells, treated versus untreated
  • organism-icon Mus musculus
  • sample-icon 2 Downloadable Samples
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Description

Comparison of LAPC cells isolated from naive PBS treated and influenza treated mice.

Publication Title

Identification of a novel antigen-presenting cell population modulating antiinfluenza type 2 immunity.

Sample Metadata Fields

Specimen part

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accession-icon GSE39562
Immortalized clonal brown, beige and white adipose cell lines
  • organism-icon Mus musculus
  • sample-icon 26 Downloadable Samples
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Description

Brown fat generates heat via the mitochondrial uncoupling protein UCP1, defending against hypothermia and obesity. Recent data suggest that there are two distinct types of brown fat: classical brown fat derived from a myf-5 cellular lineage and UCP1-positive cells that emerge in white fat from a non-myf-5 lineage. Here, we report the isolation of beige cells from murine white fat depots.

Publication Title

Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human.

Sample Metadata Fields

Cell line

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