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accession-icon GSE42050
Blocking TWEAK inhibits tumor growth through inhibition of tumor cell proliferation and survival and by enhancing the host antitumor immune response
  • organism-icon Mus musculus, Homo sapiens
  • sample-icon 16 Downloadable Samples
  • Technology Badge Icon

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part, Disease, Cell line, Race, Time

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accession-icon GSE28783
Effect of anti-miR-33 treatment on gene expression in mouse macrophages from atherosclerotic plaques.
  • organism-icon Mus musculus
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon

Description

Inhibition of miR-33 results in increased cholesterol efflux and HDL-cholesterol levels in mice. In this study we examined the effect of miR-33 inhibition in a mouse model of atherosclerosis and observed significant reduction in atherosclerotic plaque size. At the end of the study, gene expression in macrophages from the atherosclerotic plaques was assessed.

Publication Title

Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis.

Sample Metadata Fields

Sex, Specimen part

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