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accession-icon GSE109941
Lungs from mice infected with S. pneumoniae and treated with Nemiralisib
  • organism-icon Mus musculus
  • sample-icon 48 Downloadable Samples
  • Technology Badge Icon

Description

Bacterial infections cause exaserbations in COPD. Study conducted to asses the effect of Nemiralisib, a PI3Kdelta inhibitor, on S. pneumoniae infected mice

Publication Title

No associated publication

Sample Metadata Fields

Specimen part, Time

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accession-icon GSE17647
Involvement of 4E-BP1 in the protection induced by HDLs on pancreatic beta cells
  • organism-icon Mus musculus
  • sample-icon 24 Downloadable Samples
  • Technology Badge Icon

Description

High-density lipoproteins (HDLs) protect pancreatic cells against apoptosis. This property might be related to the increased risk to develop diabetes in patients with low HDL blood levels. However, the mechanisms by which HDLs protect cells are poorly characterized. Here we use a transcriptomic approach to identify genes differentially modulated by HDLs in cells subjected to apoptotic stimuli.

Publication Title

Involvement of 4E-BP1 in the protection induced by HDLs on pancreatic beta-cells.

Sample Metadata Fields

Specimen part, Cell line

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