Rod-derived Cone Viability Factor is a trophic factor of the thioredoxins family that promotes the survival of cone photoreceptors. It is encoded by the nucleoredoxin-like gene 1 Nxnl1 which also encodes by alternative splicing for RdCVFL, for a thioredoxin enzyme that interacts with the protein TAU. The role of thioredoxins in the defense mechanism against oxidation led us to examine the retinal phenotype of the Nxnl1-/- mouse after photo-oxidative stress.
No associated publication
Specimen part
View SamplesThe recent interest in the role of bone marrow derived endothelial progenitor cells in the benefits of estrogen on cardiovascular health brought us to evaluate if estrogen could affect cardiac repair more broadly by regulating biological processes involved in the functional organization of the bone marrow stem cell niche.
Estrogen-induced gene expression in bone marrow c-kit+ stem cells and stromal cells: identification of specific biological processes involved in the functional organization of the stem cell niche.
Sex, Age
View SamplesThe SAGA co-activator has been implicated in the regulation of a smal subset of genes in budding yeast in transcriptomic analyses performed in steady-state levels of RNA.
SAGA Is a General Cofactor for RNA Polymerase II Transcription.
Genetic information
View SamplesThe SAGA co-activator has been implicated in the regulation of a smal subset of genes in budding yeast in transcriptomic analyses performed in steady-state levels of RNA.
SAGA Is a General Cofactor for RNA Polymerase II Transcription.
Genetic information
View SamplesThe SAGA co-activator has been implicated in the regulation of a smal subset of genes in budding yeast in transcriptomic analyses performed in steady-state levels of RNA.
SAGA Is a General Cofactor for RNA Polymerase II Transcription.
Genetic information
View SamplesThe SAGA co-activator has been implicated in the regulation of a smal subset of genes in budding yeast in transcriptomic analyses performed in steady-state levels of RNA.
SAGA Is a General Cofactor for RNA Polymerase II Transcription.
Genetic information
View SamplesThe SAGA co-activator has been implicated in the regulation of a smal subset of genes in budding yeast in transcriptomic analyses performed in steady-state levels of RNA.
SAGA Is a General Cofactor for RNA Polymerase II Transcription.
Genetic information
View SamplesThe SAGA co-activator has been implicated in the regulation of a smal subset of genes in budding yeast in transcriptomic analyses performed in steady-state levels of RNA.
SAGA Is a General Cofactor for RNA Polymerase II Transcription.
Genetic information
View SamplesThe SAGA co-activator has been implicated in the regulation of a smal subset of genes in budding yeast in transcriptomic analyses performed in steady-state levels of RNA.
SAGA Is a General Cofactor for RNA Polymerase II Transcription.
Genetic information
View SamplesThe SAGA co-activator has been implicated in the regulation of a smal subset of genes in budding yeast in transcriptomic analyses performed in steady-state levels of RNA.
SAGA Is a General Cofactor for RNA Polymerase II Transcription.
Genetic information
View Samples