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accession-icon GSE71383
Balanced E2F transcriptional output is essential for tumor suppression in the liver
  • organism-icon Mus musculus
  • sample-icon 59 Downloadable Samples
  • Technology Badge Icon

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

E2f8 mediates tumor suppression in postnatal liver development.

Sample Metadata Fields

Age, Specimen part

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accession-icon GSE71380
E2f regulation of gene expression in the liver [1 mo]
  • organism-icon Mus musculus
  • sample-icon 59 Downloadable Samples
  • Technology Badge Icon

Description

E2Fs are regulators of the cell cycle and are involved in development. In this study we examine transcriptional changes occurring the liver in E2f1 (1KI) and E2f3b (3bKI) knock in mice. These mice have E2f1 or E2f3b knocked into the E2F3a locus resulting in loss of E2f3a and expression of E2f1 or E2f3b from the E2f3a locus as originally described In Tsai et. al., Nature 2008.

Publication Title

No associated publication

Sample Metadata Fields

Age, Specimen part

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