IL-2 signals into CD8 T cells have a programming and regulatory role in driving cells to full effector and memory differentiation. This study was designed to look for IL-2 target genes that affect CD8 T cell responses.
Endoplasmic reticulum stress regulator XBP-1 contributes to effector CD8+ T cell differentiation during acute infection.
Sex, Specimen part
View SamplesJournal : Blood. 2009 Jul 9;114(2):469-77. Epub 2009 May 13.
Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesis.
Specimen part
View Samplescompare wild type and Batf-/- B cells activated for 0 1 or 2 days in vitro.
The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells.
Specimen part
View SamplesComparative analysis can provide important insights into complex biological systems. As demonstrated in the accompanying paper, Translating Ribosome Affinity Purification (TRAP), permits comprehensive studies of translated mRNAs in genetically defined cell populations following physiological perturbations.
Application of a translational profiling approach for the comparative analysis of CNS cell types.
No sample metadata fields
View SamplesThe cellular heterogeneity of the brain confounds efforts to elucidate the biological properties of distinct neuronal populations.
No associated publication
No sample metadata fields
View SamplesThe cellular heterogeneity of the brain confounds efforts to elucidate the biological properties of distinct neuronal populations.
A translational profiling approach for the molecular characterization of CNS cell types.
No sample metadata fields
View SamplesThe cellular heterogeneity of the brain confounds efforts to elucidate the biological properties of distinct neuronal populations.
No associated publication
No sample metadata fields
View SamplesThe cellular heterogeneity of the brain confounds efforts to elucidate the biological properties of distinct neuronal populations.
A translational profiling approach for the molecular characterization of CNS cell types.
No sample metadata fields
View SamplesThe cellular heterogeneity of the brain confounds efforts to elucidate the biological properties of distinct neuronal populations.
A translational profiling approach for the molecular characterization of CNS cell types.
No sample metadata fields
View SamplesThis SuperSeries is composed of the SubSeries listed below.
Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells.
Specimen part, Disease, Treatment
View Samples