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Mus musculus
27 Downloadable Samples
Description
In a transgenic mouse model of Alzheimer disease (AD), cleavage of the amyloid precursor protein (APP) by the -secretase ADAM10 prevented amyloid plaque formation and alleviated cognitive deficits. Furthermore, there was a positive influence of ADAM10 over-expression on neurotransmitter-specific formation of synapses and on synaptic plasticity.
Publication Title
Differential gene expression in ADAM10 and mutant ADAM10 transgenic mice.
Sample Metadata Fields
Sex, Age
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GSE9460- Mus musculus
- 21 Downloadable Samples
Description
expression analysis from a genetically engineered mouse model of osteosarcoma
Publication Title
Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease.
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No sample metadata fields
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